The
hemidesmosomes "rivet" cells to the basal lamina.
The hemidesmosome. Integrins and
BPAG2 are transmembranous proteins connecting the extracellular matrix to
the intermediate filaments (red lines) and the IFs to the
actinmicrofilaments via plectin homo-dimers (purple).
References:-
Borradori, L. & Sonnenberg, A. (1996)
Hemidesmosomes: roles in adhesion, signaling and human diseases.
Curr.Op.Cell Biol. 8, 647-656.
