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An
actin-bundling protein from Dictyostelium discoideum present in filopodia
(Fechheimer, 1987),
contact regions (Fechheimer
et al, 1994)
phagosomes (Rezabek
et al, 1997;
Furukawa
& Fechheimer, 1994), the
cleavage furrow and the contractile vacuole (Haugwitz
et al, 1994).
References:-
Furukawa, R. & Fechheimer, M. (1996) Role of the Dictyostelium
30 kDa protein in actin bundle formation., Biochemistry. 35, 7224-7232.
Schlatterer, C. & Malchow, D. (1993) Intracellular
guanosine-5'-0-(3-thiotrisphosphate) blocks chemotactic motility of Dictyostelium
discoideum amoebae, Cell Mot.Cytoskel. 25, 298-307.
Fechheimer, M., Murdock, D., Carney, M. & Glover,
C. V. C. (1991) Isolation and sequenceing of cDNA clones encoding the Dictyostelium
discoideum 30,000-dalton actin bundling protein, J.Biol.Chem. 266,
2883-2889.
Fechheimer, M. (1987) The Dictyostelium discoideum
30,00-Dalton protein is an actin filament-bundling protein that is selectively
present in filopodia, J.Cell Biol. 104, 1539-1551.
Rezabek, B. L., Rodriguez-Paris, J. M., Cardelli, J. A.
& Chia, C. P. (1997) Phagosomal proteins of Dictyostelium discoideum,
J.Euk.Microbiol. 44, 284-292.
Haugwitz, M., Noegel, A. A., Karakesisoglou, J. &
Schleicher, M. (1994) Dictyostelium amoebae that lack G-actin
sequestering profilins show defects in F-actin content, cytokinesis and
development., Cell. 79, 303-314.
Furukawa, R. & Fechheimer, M. (1994) Differential
localization of a-actinin
and the 30 kD actin-bundling protein in the cleavage furrow, phagocytic cup, and
contractile vacuole of Dictyostelium discoideum, Cell Motility and
Cytoskeleton. 29, 46-56.
Fechheimer, M., Ingalls, H. M., Furukawa, R. &
Luna, E. J. (1994) Association of the Dictyostelium 30 kDa actin bundling
protein with contact regions, J. Cell Science. 107, 2393-2401.
Zigmond, S. H., Furukawa, R. & Fechheimer, M.
(1992) Inhibition of Actin Filament Depolymerization by the Dictyostelium
30,000-D Actin-bundling Protein, J.Cell Biol. 119, 559-567.
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