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Dynacortin
was originally discovered to be involved in cytokinesis of Dictyostelium amoebae
through a genetic screen (Robinson
& Spudich, 2000).
Dynacortin is now known to bind actin and to bundle actin filaments (Robinson
et al, 2002).
References:-
Robinson,
D. N. & J. A. Spudich (2000). Dynacortin, a genetic link between
equatorial contractility and global shape control discovered by library
complementation of a Dictyostelium
discoideum cytokinesis mutant. J.Cell
Biol. 150(4), 823-838.
Robinson,
D. N., Ocon, S. S., Rock, R. S. & Spudich, J. A. (2002) Dynacortin is a
novel actin bundling protein that localizes to dynamic actin structures. J.Biol.Chem.
277, 9088-9095.
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