|
A
67kd monomeric actin filament bundling protein which has two ABP-120 like actin
binding motifs (two pairs of CH domains) but has no rod-like domain. Fimbrin has two EF hands (domains
which typically bind calcium) but as no calcium sensitivity has been
demonstrated, this is of uncertain significance. Fimbrin can be phosphorylated
on serine in vivo.
References:-
Adam, T., Arpin, M., Prevost, M.-C., Gounon, P.
& Sansonetti, P. J. (1995) Cytoskeletal rearrangements and the
function role of T-plastin during entry of Shigella flexneri into
HeLa cells., J. Cell Biol. 129, 367-381.
Babb, S. G., Matsudaira, P., Sato, M., Correia,
I. & Lim, S.-S. (1997) Fimbrin in podosomes of monocyte-derived
osteoclasts, Cell Mot.Cytoskel. 37, 308-325.
Bartles, J. R. (2000) Parallel actin bundles
and their multiple actin-bundling proteins., Curr.Op.Cell Biol. 12,
72-78.
Cheng, D., Marner, J. & Rubenstein, P. A.
(1999) Interaction in vivo and in vitro between the yeast fimbrin,
SAC6P, and a polmerization-defective yeast actin (V266G and L267G)., J.Biol.Chem.
274, 35873-35880.
deArruda,
M. V.,
Watson,
S., Lin,
C.-S.,
Levitt,
J.
& Matsudaira,
P. (1990)
Fimbrin is a homologue of the cytoplasmic
phosphoprotein plastin and has domains homologous with calmodulin and
actin gelation proteins, J.
Cell Biol. 111,
1069-1079.
Ezzell, R. M., Chafel, M. M. & Matsudaira,
P. T. (1989) Differential localization of villin and fimbrin during
development of the mouse visceral endoderm and intestinal epithelium., Development.
106, 407-419.
Ezzell, R. M., Leung, J., Collins, K., Chafel,
M. M., Cardozo, T. J. & Matsudaira, P. T. (1992) Expression and
Localization of Villin, Fimbrin, and Myosin I in Differentiating Mouse
F9 Teratocarcinoma Cells., Developmental Biol. 151, 575-585.
Fukui, Y., de Hostos, E., Yumura, S.,
Kitanishi-Yumura, T. & Inoué, S. (1999) Architectural dynamics of
F-actin in eupodia suggests their role in invasive locomotion in Dictyostelium.,
Exp.Cell Res. 249, 33-45.
Hanein, D., Matsudaira, P. & DeRosier, D.
J. (1997) Evidence for a conformational change in actin induced by
fimbrin (N375) binding., J.Cell Biol. 139, 387-396.
Hisano, T., Ono, M., Nakayama, M., Naito, S.,
Kuwano, M. & Wada, M. (1996) Increased expression of T-plastin gene
in cisplatin-resistant human cancer cells: identification by mRNA
differential display., FEBS letters. 397, 101-107.
Honts, J. E., Sandrock, T. S., Brower, S. M.,
O'Dell, J. L. & Adams, A. E. M. (1994) Actin mutations that show
suppression with fimbrin mutations identify a likely fimbrin-binding
site on actin, J. Cell Biol. 126, 413-422.
Jones, S. L. & Brown, E. J. (1996) FcgRII-mediated
adhesion and phagocytosis induce L-plastin
phosphorylation in human neutrophils., J.Biol.Chem. 271,
14623-14630.
Jones, S. L., Wang, J., Turck, C. W. &
Brown, E. J. (1998) A role for actin-bundling protein L-plastin in the
regulation of leukocyte integrin function., Proc.Nat.Acad.Sci. USA.
95, 9331-9336.
Karpova, T. S., Tatchell, K. & Cooper, J.
A. (1995) Actin filaments in yeast are unstable in the absence of
capping protein or fimbrin, J. Cell Biol. 131, 1483-1493.
Kocks, C. & Cossart, P. (1993) Directional
actin assembly by listeria-monocytogenes at the site of polar surface
expression of the acta gene-product invllving the actin-bundling protein
plastin (fimbrin), Infectious Agents And Disease Reviews Issues And
Commentary. 2, 207-209.
Kovar, D. R., Gibbon, B. C., McCurdy, D. W.
& Staiger, C. J. (2001) Fluorescently-labeled fimbrin decorates a
dynamic actin filament network in living plant cells., Planta. 213,
390-395.
Lollike, K., Johnsen, A. H., Durussel, I.,
Borregaard, N. & Cox, J. A. (2001) Biochemical characterization of
the penta-EF-hand protein grancalcin and identification of L-plastin as
a binding partner., J. Biol.Chem. 276, 17762-17769.
Matsudaira, P. (1994) The fimbrin and
alpha-actinin footprint on actin, J. Cell Biol. 126, 285-287.
Nakano, K., Satoh, K., Morimatsu, A., Ohnuma,
M. & Mabuchi, I. (2001) Interactions among a fimbrin, a capping
protein, and an actin-depolymerizing factor in organization of the
fission yeast actin cytoskeleton., Mol.Biol.Cell. 12, 3515-3526.
Prévost, M. C., Lesourd, M., Arpin, M., Vernel,
F., Mounier, J., Hellio, R. & Sansonetti, P. J. (1992) Unipolar
reorganization of F-actin layer at bacterial division and bundling of
actin filaments by plastin correlate with movement of Shigella
flexneri within HeLa cells., Infection and Immunity. 60,
4088-4099.
Rosales, C., Jones, S. L., McCourt, D. &
Brown, E. J. (1994) Bromophenacyl bromide binding to the actin-bundling
protein 1-plastin inhibits inositol trisphosphate-independent increase
in Ca2+ in human neutrophils, Cell Biology. 91,
3534-3538.
Volkmann, N., DeRosier, D. J., Matsudaira, P.
& Hanein, D. (2001) An atomic modelof actin filaments cross-linked
by fimbrin and its implications for bundle assembly and function., J.Cell
Biol. 153, 947-956.
Wang, J. & Brown, E. J. (1999) Immune
complex-induced intgrin activation and L-plastin phosphorylation require
protein kinase A., J.Biol.Chem. 274, 24349-24356.
Wang, J., Chen, H. & Brown, E. J. (2001) L-plastin
peptide activation of avb3-mediated
adhesion requires integrin conformational change and actin filament
disassembly., J.Biol.Chem. 276, 14474-14481.
Watanabe, A., Yonemura, I., Gonda, K. &
Numata, O. (2000) Cloning and sequencing of the gene for a Tetrahymena
fimbrin-like protein., J.Biochem. 127, 85-94.
Wu, J.-Q., Bahler, J. & Pringle, J. R.
(2001) Roles of a fimbrin and an a-actinin-like
protein in fission yeast cell polarization and cytokinesis., Mol.Biol.Cell.
12, 1061-1077.
Zhou, D., Mooseker, M. S. & Galán, J. E.
(1999) An invasion-associated Salmonella protein modulates the
actin-bundling activity of plastin., PNAS. 96, 10176-10181. |
