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A
member of the ERM (Ezrin, Radixin, Moesin) group of proteins (see ERM
page) whose C terminal
half (approximately) is homologous to the membrane associated region of
the band 4.1 super-family (Fig 1a). Ezrin associates with a number of
membranous proteins such as CD44, CD43 at the cytoplasmic face of the
plasma-membrane. It is especially abundant in the placenta.
References:-
Bretscher,
A. (1999). "Regulation of cortical structure by ezrin-radixin-moesin
protein family." Curr.Op.Cell Biol. 11, 109-116.
Crepaldi, T., A.
Gautreau, et al. (1997). "Ezrin
is an effector of hepatocyte growth factor-mediated migration and morphogenesis
in epithelial cells." J.Cell Biol. 138(2), 423-434.
Mangeat,
P., Roy, C. & Martin, M. (1999). "ERM proteins in cell adhesion and
membrane dynamics." Trends Cell Biology 9, 187-192.
Tsukita,
S., Yonemura,S. & Tsukita, S. (1997)."ERM (ezrin/radixin/moesin)
family: from cytoskeleton to signal transduction." Curr.Biol. 9,
70-75.
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