| Like
the other elongation factors, EF-1a
and EF2, EF-1b
has been found to be an actin binding protein (Furukawa
et al, 2001).
In Dictyostelium EF-1b
has a similar distribution as EF-1a
having diffuse cytoplasmic staining with concentration at the F-actin
rich cortical region especially the leading edge (Furukawa
et al, 2001).
Low concentrations of EF-1b
increase
the rate of spontaneous actin polymerization at pH 8.0, but higher
concentration reversed this effect. Complexes of wheat germ EF-1bg
also stimulated actin polymerization in vitro.
References:-
Furukawa, R., Jinks, T. M., Tishgarten,
T., Mazzawi, M., Morris, D. R. & Fechheimer, M. (2001) Elongation
factor 1b is an actin-binding protein., BBA.
1527, 130-140. |
